informed by feedback from the Committee for Medicinal Products for Human Use of the European Medicines Agency.” Back in September, disappointing results from the clinical trial on which the application was based dented AstraZeneca’s share price. Shares of the company were last up 0.7% at 9:57 a.m. London time. Overnight in Asia, stocks were in mixed territory as investors monitored the monetary policy outlook in Japan, the blockbuster merger between autos giants Honda and Nissan and faltering consumer confidence in South Korea. Trading is expected to be muted across the globe this week as multiple markets close early on Tuesday and will remain shuttered on Wednesday for Christmas Day.